Ngā Rauropi Whakaoranga

Polygodial isolated from East African plants (Warburgia species). The observation of cell membrane lesions led authors to hypothesis: use of polygodial to facilitate the transmembrane transport of exogenous chemicals into cells. E.g. Polygodial and antibiotic with poor cell membrane permability - antibiotic effect could be increased if it could gain better entrance into a cell. Polygodial as "advance scout". A remarkably enhanced efficacy obtained when actinomycin D used in combination with polygodial.

(N.B. Polygodial is an active principle in Pseudowintera colorata, horopito)