Copy a link to this page Cite this record

Kubo I., Tangiguchi M. 1988. Polygodial, an antifungal potentiator. Journal of Natural Products 51(1): 22-29

Reference document

Click to collapse Notes Info

Polygodial isolated from East African plants (Warburgia species). The observation of cell membrane lesions led authors to hypothesis: use of polygodial to facilitate the transmembrane transport of exogenous chemicals into cells. E.g. Polygodial and antibiotic with poor cell membrane permability - antibiotic effect could be increased if it could gain better entrance into a cell. Polygodial as "advance scout". A remarkably enhanced efficacy obtained when actinomycin D used in combination with polygodial.

(N.B. Polygodial is an active principle in Pseudowintera colorata, horopito)

Click to collapse Related records Info

Click to collapse Bibliographic details Info

Polygodial, an antifungal potentiator

Kubo I., Tangiguchi M.
Journal of Natural Products

Click to collapse Metadata Info

12 June 2007
8 July 2020
Click to go back to the top of the page